Number of Pages : 19
Current Page : 19
Total number of records : 918
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Visual Histology
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Visual Histology streaming videos
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Visualization of Transcription Factor Interactions in Living Cells - (Henry Stewart Talks)
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Transcription regulatory proteins; Combinatorial control of gene expression; Visualization of transcription factor interactions and modifications in living cells; New methods development; Bimolecular fluorescence complementation (BiFC) assays
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Visualizing and manipulating phosphoinositide and phospholipid signaling - (Henry Stewart Talks)
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Making/using phosphoinositide phosphate (PIP) affinity probes; Effects of exogenous PIPs; Metabolically-stabilized PIPs; New tethering strategies; Signaling proteomics; Antibodies to PIPs; Visualizing phospholipase A and D activity with fluorogenic probes
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Vitamin D and prostate cancer - (Henry Stewart Talks)
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"Vitamin D actions: classical view and expanded view; Vitamin D metabolic pathways; Vitamin D and cancers; Vitamin D-deficiency hypothesis; Sunlight, vitamin D and prostate cancer risk; Importance of local production of calcitriol"
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Vitamin D Endocrine System: Basics - (Henry Stewart Talks)
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What is a vitamin?; What is a hormone?; Vitamin D biology fundamentals; Calcium homeostasis; Classical biological actions of vitamin D; Vitamin D and endocrine system; Key discoveries in the field; Kidney as an endocrine gland for hormone-D
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Vitamin D Endocrine System: Mechanisms to Produce Biological Responses - (Henry Stewart Talks)
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"Optimal ligand shapes; Modes of action of hormone-D; Shape of ligand for VDRNUC; Three dimensional shape of the VDR; Shape of ligand for DBP; DBP structure domains A, B, C; Shape of ligand for rapid responses; Steroid receptor superfamily"
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Vitamin D Endocrine System: VDR Binding, Nutrition and Drugs Development - (Henry Stewart Talks)
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VDR conformational ensemble; A vitamin D receptor ensemble model; X-ray crystal structure of the nuclear vitamin D receptor; VDR G- and A-pocket; Vitamin D nutrition for good health; Sources of vitamin D; How much vitamin D do we need?
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Vitamin E regulation: mechanisms to control plasma atocopherol concentrations - (Henry Stewart Talks)
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Factors that alter vitamin E status in humans; Oxidative stress and vitamin E; Vitamin E pharmacokinetics and metabolism; Xenobiotic metabolism
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Voltage-Dependent Calcium Channels - (Henry Stewart Talks)
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Introduction to voltage-gated calcium channels; Correlation of known structural features to function; Subtypes of calcium channels and their physiological correlates; Pharmacology of voltage-gated calcium channels
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What Causes Primary Biliary Cirrhosis? - (Henry Stewart Talks)
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Primary biliary cirrhosis (PBC): pathology and serological characteristics; Etiology: genetic and environmental factors; Mitochondrial antigens of PBC; Do autoreactive T cells play a role in the pathogenesis of PBC?
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What to do in Therapy in the Face of HIV Drug Resistance? - (Henry Stewart Talks)
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Drug resistance in HIV disease can occur for each drug used in therapy; Drug resistant forms of HIV can be sexually transmitted; Drug resistance can be selected by antiviral drugs; HIV mutations can interact with one another to affect phenotype
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Whole-genome association studies: practical advice and considerations - (Henry Stewart Talks)
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What are whole-genome (genome-wide) association studies and why do them?; Steps in WGA study; HIV setpoint; Phenotype definition; Setpoint; Whole genome genotyping panels; PLINK; Cryptic population stratification; PCA and EIGENSTRAT
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Why Medicine Needs Evolutionary Biology - (Henry Stewart Talks)
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"How evolution is useful to medicine; Why doctors don't know evolution; The body: perfect and pathetically flawed; Proximate and evolutionary explanations; Explain vulnerability, not diseases; Six reasons for vulnerability; Darwinian medicine growing fast"
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Why we Cook with Spices: Preventative Darwinian Medicine - (Henry Stewart Talks)
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Evolution of chemicals that give spices their unique flavors; All spices have antimicrobial properties; Use of spices in human cultures; Foodborne illnesses;
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Widespread Structural Variations in the Human Genome - (Henry Stewart Talks)
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Genetic differences and similarities between normal individuals; Single Nucleotide Polymorphisms (SNPs); Structural variants in human genome; Comparative Genomic Hybridization (CGH); Clinical genetic diagnostics; Copy Number Variation (CNV); Overlapping
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Yeast and fungal prions: a help or a hindrance? - (Henry Stewart Talks)
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[URE3] and [PSI+] not found in wild strains indicating they are harmful; [Het-s] may benefit its host or may result from “meiotic drive”; Some “prion domains” cannot be prions; “Prion domains” have non-prion functions
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Yeast plasmid: a highly persistent selfish DNA element - (Henry Stewart Talks)
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The yeast plasmid as a highly optimized design for a multi-copy selfish DNA element; The need for an active partitioning system for the segregation of a high copy plasmid; Coupling between plasmid segregation and chromosome segregation
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Yeast prions and protein chaperones - (Henry Stewart Talks)
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Role of protein chaperones in protein folding; Yeast prions as amyloid forms of cellular proteins; Requirement of chaperone machinery for prion propagation; Chaperone mutants adversely affect prions and provide insight into chaperone/amyloid interactions
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